Home / Home

Biliary Tract Cancer Research

Biliary tract cancer research focuses on chemoimmunotherapy combinations, FGFR2 and IDH1-directed targeted therapy, and molecular profiling of cholangiocarcinoma subtypes.

Our Biliary Tract Cancer Analysis

  • July 9, 2026JAMA OncologyTOPAZ-1 (NCT03875235)

    Durvalumab Plus Chemotherapy Sustains Survival Benefit at 4 Years in Advanced Biliary Tract Cancer: Final Analysis of the Phase 3 TOPAZ-1 Trial

    Final post hoc analysis of the global, double-blind, placebo-controlled phase 3 TOPAZ-1 trial (685 patients randomized 1:1) reporting the longest published follow-up — approximately 4 years — of an immunotherapy-plus-chemotherapy regimen in first-line advanced biliary tract cancer (aBTC)